Відео

perfectly explained

sir please share the link of autodock4 autogrid 4.. the link is not working

Tysm sir😊

Hello Sir, in Openbabel I selected the sdf - - MDL MOL format to upload my 2D ligand but in output the pdbqt format is not displayed. There is just pdb format. My ligand is simply a cadmium ion and the protein is IVQQ present in Streptococcus pneumoniae. If I convert sdf to pdb format the ligand file is not getting opened in Autodock. To which format should I convert the ligand sir? Thank you

Sir aftr entering the ligand file name in the CMD, It is only showing the list of PDBQT files in the ligand.txt file. Vina is not running

If I may know why did you select a specific chain

sir, can you tell which scoring is used in this method, AutoDock 4 or Vian scoring function?

Hello, how does HEX do macro docking? I need your help.

Thank you Dr BB, for this video and taking time to share your expertise. You’re making a huge global impact. Best regards, Ayo (Nigeria)

Thanks for your precious information 🙏🏻♥️

finally i got my output with your tutorial, thank you sir... but i haven't get any rmd table in dlg file and i have get no more hydrogen bonds are created in analyzing conformations, may i know the reason sir and please tell me how to rectify it

beautifully done

Sir one request : plz suggest some list of good laptops for doing molecular docking project!!!🙏🏻🙏🏻🙏🏻

If you are a long time Linux/*nix user, you may backport latest gromacs from Debian Sid repository and rebuild it from the sources.

the music in the background of the video so annoying , id appracite to you is you make it without music so we can foucs on the explination well

Hi, why did you predict the transmembrane region?what is it's importance?

If you don't have coding experience or a powerful computer, you can use QuandleLabs to use all of the above tools completely online

Autogrid is not running and glg file is also not generated any solution. please help

Dear sir can you please teach me separately in Google meet for downloading the structure of protein protein interaction??

Nice

Excuse, i want to ask if i am not working on gene cloning; rather, I am conducting gene expression experiments. How can I avoid incomplete gene amplification when designing primers?

Can we run in Intel gpu

Good morning sir, I am Manohar Naik your Junior in sku from Kadiri sir , I have a doubt how can I contact you sir I have no number sir

Sir g You are the only one who not work for only to get views but to help someone

great sir thank you, the links in the description are more precious

Sir which software is used to predict the anti-cancer compound ?

3h42 and 3m0c are in complex. did you seprate them before?

why did you use hex when it was non validated

Sir , what if the ligand is not inserted to the protein

After this step, how to get 2D interactions?

I'm getting an error during running autogrid4, it's not running.

From where autogrid4 comes, I'm confused

Great video, Thanks alot and this the best lecture in docking that i have ever seen. but my question: What is the purpose of the step taken @9:10, changing the histidine hydrogens? why not +1? and why you didnt apply force field for the compounds?

Can you please tell me how to run gromacs in could Google colab platform

The best video on UA-cam... thank you very much sir

Please share videos on network pharmacology, QASR and DFT for drug discovery

Fucking hindu your video and social media is a bullshit, and your teaching is boring and deficint

You just saved my undergraduate thesis research. Thank you so much!!

Im performing docking on a known active site so i limited the gridbox around the active site only. Some of the conformations i got after docking were outside the grid box. Is that normal?

Thank you so much for this helpful tutorial! I am having an issue if I can ask. When I run the command, the cmd says that access is denied.

Hi, sir , this video is very helpful to understand molecular docking with binding active site. My question is "How to know active binding site of any other protein for good result of molecular docking?????"

Thanks

Exellent ❤

Thank you professor, I want linearized vector it has 7000 basepair. I tried restrictions enzyme, but I can't find valid enzyme.so I want to make primer. Please guide me. I also tried to make primers but I can't fullfil the condition of tm, gc and no of basepair. How can I do.

sir when i want to save the GPF then i get error and shows that you must select macromolecule before writing gpf

This was SO MUCH helpful!! Thank you for the amazing explanation!

this video is a waste of time, dont even bother with it. theres thousands of better options out there

Sir Good evening sir I'm Manohar Naik from Kadiri ,your junior in SKU I have a doubt sir

When I read a paper about andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach. The andrographolide compound has a free energy of -3.09 Kcal/mol, but it shows great binding when compared to other compounds having more negative free energy values. I think about pressure, temperature, and pH in the body affecting the inhibitory process

Make a clear cut video of cuda installation with gromacs why you skip that portion?